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Autoimmune Skin Conditions

Your Immune System Isn't Broken. It Just Needs Precise Direction.

Autoimmune skin diseases are among the most complex and misunderstood conditions in medicine. I evaluate your full inflammatory history — down to the genetic level when necessary — to identify exactly what's driving your disease and target it with precision.

Book an Autoimmune Skin Consultation
Autoimmune skin condition consultation
Who This Is For

For Patients Who Know Something Deeper Is Going On.

Autoimmune skin disease patients often share a common experience: multiple specialists, multiple diagnoses, and a growing sense that each doctor is treating one piece of a larger puzzle without anyone seeing the whole picture.

I see the whole picture. I evaluate the full arc of your immune history — not just your current condition — to understand which pathways are involved, whether there's a genetic component, and whether your body may be predisposed to additional immune events in the future.

Conditions I Treat

Precise Diagnosis. Targeted Treatment.

Each autoimmune skin condition involves different immune pathways. Identifying which ones are driving your disease is the first step to treating it effectively.

Vitiligo

Loss of skin pigmentation caused by immune-mediated destruction of melanocytes. Treated with targeted therapies that suppress the specific immune response responsible. New JAK inhibitor-based treatments have significantly changed what's possible for vitiligo patients.

World-leading expert

Alopecia Areata

An autoimmune condition where the immune system loses tolerance to hair follicles, causing patchy or complete hair loss. I am one of the world's leading experts and prescribers of JAK inhibitors to achieve remission.

Lichen Planus

A chronic inflammatory condition affecting skin, nails, and mucous membranes. Has both immune and metabolic drivers depending on the patient. I evaluate both dimensions.

Published research

Complex & Overlapping Autoimmune Disease

Some patients present with multiple autoimmune conditions or recurring immune events across different organ systems. This may indicate an inborn error of immunity — a genetic immune dysregulation. I have published research in this area and evaluate for it specifically when the clinical picture suggests it. I also evaluate bullous pemphigoid and other complex autoimmune blistering conditions.

Dr. Bordone evaluating autoimmune history
My Approach

From the Immune System Up — Not Just the Skin Down.

My evaluation begins long before the current diagnosis. I review your full immune history: birth and early development, childhood hospitalizations, food allergies, family patterns of immune or inflammatory disease.

This history tells me which immune pathway is most likely involved. I distinguish between TH1-driven responses — classic autoimmune disease like vitiligo, psoriasis, and celiac — and TH2-driven responses, which present more like allergic and atopic disease: eczema, hives, asthma. The distinction matters because they respond to different treatments.

When a patient has both types simultaneously, severe disease, or a family history that suggests a pattern, I order genetic testing to look for an inborn error of immunity. Identifying one changes treatment fundamentally — and informs cancer screening, because some genetic immune conditions carry elevated cancer risk.

What to Expect

Your First Consultation: A History That Actually Goes Back Far Enough.

01

Before the Appointment

Send any prior biopsy results, lab work, or specialist notes. Records from childhood illnesses or past immune events — even from other specialists — can be valuable.

02

During the Consultation

I take an extensive immune history that most patients have never been asked to provide. I review your current condition, prior treatments and responses, and build a detailed picture of your immune system across your lifetime — including your family history in depth.

03

Lab Work & Genetic Testing

Based on the evaluation, I order targeted labs and, when indicated, genetic testing. Results are reviewed in a follow-up consultation with a full explanation of findings and next steps.

Frequently Asked Questions

Answers Before Your First Consultation

It depends on the specific condition and what's driving it. Many autoimmune skin diseases can be effectively stabilized — and in some cases significantly improved — with targeted treatment. The key is identifying which pathways are involved and addressing them precisely. I'll give you an honest trajectory based on your specific case.

Patients with one autoimmune condition have a higher baseline risk of developing others driven by the same immune pathway. I evaluate this risk as part of my workup. For patients with genetic immune dysregulation, understanding the full picture allows for proactive monitoring.

Inborn errors of immunity are genetic variants that affect how the immune system is regulated. They don't always cause severe illness — some cause chronic inflammatory conditions without obvious immune deficiency. I test for these when the clinical picture suggests an underlying genetic component: multiple autoimmune conditions, severe or treatment-resistant disease, or a significant family history.

Yes — JAK inhibitors target immune pathways shared across multiple conditions. For patients with overlapping autoimmune disease, a single well-chosen JAK inhibitor may address several issues simultaneously. I have extensive experience with these medications and will assess whether they're appropriate for your specific case.

Ready for an Evaluation That Looks at the Full Immune Picture?

I'm accepting new patients via telehealth in NY, NJ, FL, and AZ. New patient visits from $375.

Book an Autoimmune Skin Consultation